Global trial to test whether MMR vaccine protects front-line health-care workers against COVID-19

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Vaccine may strengthen immune response to viral infections; trial to enroll up to 30,000 health-care workers

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An international research network of physicians and scientists is launching a clinical trial to evaluate whether the vaccine for measles, mumps and rubella (MMR) can protect front-line health-care workers against infection from SARS-CoV-2, the virus that causes COVID-19. The trial aims to enroll up to 30,000 health-care workers globally.

Washington University School of Medicine in St. Louis is the clinical coordinating center for this ambitious, international trial, which is the first to evaluate on a large scale whether the MMR vaccine can protect against COVID-19. The trial is co-led by Washington University, University College London

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Coronavirus: Donald Trump in hospital after positive Covid-19 test

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Why people are worried about President Donald Trump and coronavirus?

US President Donald Trump remains in hospital for treatment after testing positive for coronavirus.

The President was flown to a military hospital on Friday 2 October and a spokesperson from the White House said Mr Trump “was fatigued but in good spirits” and his doctor said “the president is doing very well.”

There have however, been concerns over comments made by his doctors that he could return home on Monday 5 October.

This is because it has been revealed that his condition might be more serious than previously thought. It has been reported that he has received extra oxygen twice, and taken the steroid treatment dexamethasone, which is normally only given to serious cases, according to experts.

On Sunday, President Trump made a

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MattDoesFitness Tries the Pacer Fitness Test Without Training

British bodybuilder and YouTuber Matt Morsia, a.k.a. MattDoesFitness is game to try any type of fitness challenge. He’s already taken on the British Army Fitness Test, the Russian Army Fitness Test, and the U.S. Air Force’s Physical Fitness Test (PFT) . For his latest challenge, he’s taking on the PACER fitness test, along with his brother Ben.

You might be familiar with the test as the beep test, or the multi-stage fitness test. “There are multiple names for it, but there is one universal description: it f*cking sucks,” Morsia says.

PACER stands for Progressive Aerobic Cardiovascular Endurance Run, and the test is used to gauge aerobic capacity for everyone from elementary schoolers to pro athletes. During the test, you run 20 meter shuttles back and forth, trying to get to the other side before you hear a ‘beep’. The beeps get faster and faster—and once you can’t complete the shuttle

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UChicago Medicine launches clinical trial to test the potential of antibody against SARS-CoV-2

The University of Chicago Medicine is launching a clinical trial to examine the potential of an antibody against the SARS-CoV-2 spike protein for treating COVID-19, the disease caused by the novel coronavirus.

For the BLAZE-1 trial, UChicago is recruiting 22 participants to be treated with the LY-CoV555 antibody developed by Eli Lilly and Company in collaboration with AbCellera. The antibody was first identified by scientists at the National Institute of Allergy and Infectious Diseases and AbCellera in a blood sample from a U.S. patient who had recovered from COVID-19.

The neutralizing monoclonal antibody targets and binds to the spike protein on the surface of the SARS-CoV-2 virus, preventing it from attaching and entering into human cells. Without access to cells, the virus can’t replicate.

There is data showing that the LY-CoV555 antibody can block the virus from replicating in cells in

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Italy’s Berlusconi taken to hospital after positive coronavirus test

ROME (Reuters) – Italy’s former prime minister, Silvio Berlusconi, has been admitted to hospital in Milan for further checks after testing positive for the new coronavirus, his Forza Italia party said on Friday.

The party said his medical condition was not a cause for concern.

The 83-year-old-media tycoon had been in isolation in his house in the town of Arcore, north of Milan.

Forza Italia said he was now at the San Raffaele Hospital “as a precaution”.

Berlusconi had spoken via video link to a meeting of Forza Italia supporters on Thursday and said his fever had passed.

“I no longer have fever, nor pain, I want to reassure everyone that I am quite well,” he said.

Berlusconi decided to test for COVID-19 after having a holiday in Sardinia, his personal physician said.

The Mediterranean island suffered a sharp increase in COVID-19 cases in August as tourists descended on its

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IU School of Medicine to test experimental COVID-19 vaccine


INDIANAPOLIS (AP) — The Indiana University School of Medicine announced Thursday that it’s seeking up to 1,500 volunteers to take part in a late-stage clinical trial of an experimental COVID-19 vaccine.

The medical school is one of 81 sites in the U.S. — and the only one in Indiana — chosen to test the vaccine developed by British drugmaker AstraZeneca in partnership with Oxford University.

Nationwide, researchers plan to enroll a total of 30,000 participants for the clinical trial of the Cambridge, England-based company’s vaccine, known as AZD1222. Two-thirds of the participants will receive the vaccine and the remaining one-third will get a placebo.

IU’s vaccine testing will be conducted at IU Health University Hospital, located in Indianapolis. The Phase III trial is the last stage before manufacturers can seek the Food and Drug Administration’s approval for widespread public use.

Dr. Cynthia

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Foundation Medicine wins FDA OK for pan-cancer liquid biopsy test

The Food and Drug Administration on Wednesday approved a comprehensive “liquid biopsy” platform that can detect multiple kinds of cancer and genomic alterations from pieces of tumor DNA circulating in a patient’s blood. The Foundation Medicine test, designed to identify specific types of cancer and match patients’ mutations to genetically targeted therapies, joins one approved earlier this month developed by Guardant Health.

The FDA has previously approved liquid biopsy tests for individual cancers and as so-called companion diagnostics, which identify whether patients are likely to benefit from a specific targeted drug. Foundation Medicine, a Cambridge, Mass., unit of Swiss biopharma Roche (RHBBY), has won the agency’s second nod for a pan-cancer blood assay, which combines liquid biopsy with other kinds of testing to find more diagnostic and genomic biomarkers.

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Foundation Medicine’s cancer-profiling blood test approved by FDA

The FDA has approved Foundation Medicine’s liquid biopsy blood test, allowing oncologists to profile the genomic mutations found within any solid tumor without needing to remove and analyze small slices of tissue, and to help assign an individual cancer patient their most correct treatment.

The comprehensive FoundationOne Liquid CDx test returns reports on more than 300 alterations in cancer-related genes, as well as biomarkers such as tumor mutational burden and microsatellite instability to predict a person’s response to certain therapies.

“Many cancer patients are unable to have a tissue biopsy,” said Foundation Medicine co-founder Levi Garraway, who currently serves as chief medical officer and head of global product development at Roche, its corporate parent.

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Yale School of Medicine and hospital to test new coronavirus vaccine

NEW HAVEN — Yale School of Medicine and Yale New Haven Hospital announced the start of Phase 3 of the Pfizer coronavirus vaccine trial at the hospital that will draw participants from across the country.

The hospital and medical school trial of Pfizer’s treatment vaccine candidate is part of a massive effort that will

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Diversity, Not Test Scores, Equals Quality in Medicine

Quinn Capers IV, MD, a professor of cardiovascular medicine and vice dean for faculty affairs at The Ohio State University has long advocated for increased diversity in medicine and for physicians to be activists.

As protests broke out across the globe in response to the killing of George Floyd, Capers sent out a tweet to inspire Black boys who want to be doctors, but may lack visible role models.

Medscape caught up with the interventional cardiologist. Our original interview was conducted before the recent controversy over a paper in the Journal

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